Zopiclone: A Third Generation of Hypnotics
نویسندگان
چکیده
منابع مشابه
Zopiclone, a third generation of hypnotics.
Many years ago now the benzodiaze-pines began to replace the barbiturates, but, when we think about this change and remember that the barbiturates were probably being used in unnecessarily high doses, the therapeutic advantage of the benzodiaze-pines may not have been so great as it appeared at the time. The major advance was that of increased safety in overdosage. Initially, the benzodiazepine...
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AIMS The non-benzodiazepine hypnotics zolpidem and zopiclone, which are indicated for short-term treatment of insomnia, were considered originally by physicians as almost devoid of abuse and dependence potential. Several recent publications, however, have suggested that both agents carry a significant risk of abuse. To substantiate and re-evaluate this situation, the world literature was review...
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BACKGROUND Benzodiazepines and related drugs affect physical functioning negatively and increase fall and fracture risk. As impaired muscle strength and balance are risk factors for falls, we examined the effects of hypnotic withdrawal on handgrip strength and balance in older adult outpatients during and after long-term use of temazepam, zopiclone and zolpidem (here collectively referred to as...
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ژورنال
عنوان ژورنال: Pharmacology
سال: 1983
ISSN: 1423-0313,0031-7012
DOI: 10.1159/000137907